Description
MOTS-C | Product Description
MOTS-c | Introduction
MOTS-c is a 16-amino-acid mitochondrial-derived peptide used in RUO bioenergetic models to probe metabolic regulation and stress adaptation. Studies evaluate folate–purine–AMPK pathway interactions, glucose handling, and adaptive gene programs under metabolic stress. Not intended for diagnostic or therapeutic use.
- AMPK-linked energy regulation assays
- Metabolic stress response and gene programs
- Insulin sensitivity & mitochondrial signaling models
MOTS-c | Molecular Identity & Composition
| Name | MOTS-c |
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (MRWQEMGYIFYPRKLR) |
| Molecular Formula | C101H152N28O22S2 |
| Molecular Weight | 2174.6 g/mol |
| CAS Number | 1627580-64-6 |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile or bacteriostatic water |
| Purity | ≥95–99% (HPLC), lot-specific |
| Storage Guidelines | • Lyophilized: ≤0°F (–18°C) to −4°F (−20°C), desiccated • Reconstituted: 36–46°F (2–8°C); short-term only • Long-Term: Store dry at ≤−20°C; avoid freeze–thaw |
LuvionBio Quality Advantage
- Purity & Identity: ≥99% | HPLC & MS validated
- Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
- Stability & Process: Controlled-nucleation lyophilization | Stability-focused procedures
- Formulation & QA: PhD-formulated | GMP / ISO-aligned manufacturing
- Packaging: Luxe Fridge-Ready Box
Category Overview | Bioenergetic Pathway Modulators
Bioenergetic peptides are used in RUO studies to explore how cells generate, manage, and recover energy. These compounds interact with key metabolic pathways—especially mitochondrial ATP output and redox signaling—making them essential tools for researchers investigating energy dysfunction, oxidative stress, and cell viability under stress conditions.
Exciting Areas of Study
- Modulation of ATP output in energy-restricted cellular environments.
- Pre-clinical insights into mitochondrial performance.
- Stress-induced metabolic pathway behavior in controlled assays.
- Early-stage models of energy dysregulation across tissue types.
- Insulin sensitivity & glucose regulation in cell-based assays.
Research Applications
- Map links between mitochondrial health and system-level decline
- Assess peptide influence on cellular energy balance and efficiency
- Examine how metabolic flexibility contributes to tissue regeneration
MOTS-c | Research Modeling & Applications
- Probe AMPK activation and downstream bioenergetics
- Model insulin sensitivity and substrate utilization
- Assess stress-adaptive transcriptional programs
Research Use Disclaimer
This product is intended solely for laboratory research purposes and is not suitable for human, animal, or household use. Researchers must follow institutional safety protocols. See our
Terms & Conditions and Research Compliance Disclaimers for details.





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